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Toronto Blue Jays vs Tampa Bay Rays Odds, Spread, and Totals

The Toronto Blue Jays will look to keep their winning ways going against the Tampa Bay Rays tonight. The Blue Jays have rattled off five straight wins, a streak that…

TAMPA, FLORIDA - SEPTEMBER 15: Chandler Simpson #14 of the Tampa Bay Rays rounds third base to score on an RBI double off the bat of Yandy Díaz (not pictured) in the first inning against the Toronto Blue Jays at George M. Steinbrenner Field on September 15, 2025 in Tampa, Florida.
Julio Aguilar/Getty Images

The Toronto Blue Jays will look to keep their winning ways going against the Tampa Bay Rays tonight. The Blue Jays have rattled off five straight wins, a streak that has helped entrench them as the AL East's leader. The Rays, on the other hand, have lost eight of their last 10 games, tumbling down the AL Wild Card rankings in the process. 

A quality starting pitching situation should allow the Jays a realistic shot at continuing their streak. Veteran Jose Berrios has put together a solid, if unspectacular campaign, earning a 3.99 ERA and a 1.29 WHIP to go with it. However, in his two starts against the Rays, he put together less-than-stellar outings, with one such appearance ending after the righty allowed five runs in as many innings. This matchup represents a good chance for Berrios to get back on the horse and play well against a team he has struggled with in the recent past.

The Rays will count on starting pitcher Ryan Pepiot tonight. That has typically been a fantastic thing for the Rays thanks to Pepiot's 3.59 ERA and 1.13 WHIP. Unlike Berrios, Pepiot has a solid history against a menacing Toronto lineup, having held the Jays scoreless over seven frames the last time he was dealt this matchup. A repeat performance would give the struggling Rays a chance to jump back into the win column.

Spread

  • Blue Jays -1.5 (+144)
  • Rays +1.5 (-179)

Moneyline

  • Blue Jays -105
  • Rays -104

Totals

  • OVER 8.5 (-102)
  • UNDER 8.5 (-113)

*The above data was collected on Sept. 16, 2025, and may have changed since writing.

  • The Blue Jays are 85-65 ATS this season.
  • The Blue Jays are 25-18 ATS when facing a divisional opponent.
  • The OVER is 38-33-4 when Toronto plays on the road.
  • The Rays are 75-75 ATS this year.
  • The Rays are 30-45 ATS when they play at home.
  • The UNDER is 21-17-2 when Tampa Bay plays an AL East opponent.

Blue Jays vs Rays Injury Reports

Toronto Blue Jays

  • Bo Bichette, SS - Out
  • Anthony Santander, DH - Out

Tampa Bay Rays

  • Jonathan Aranda, 1B - Out
  • Christopher Morel, UTIL - Day-to-Day
  • Taylor Walls, SS - Out

Blue Jays vs Rays Prediction and Pick

It is a shock to see that the Blue Jays are at plus money here. Toronto has been firing on all cylinders lately, and the opposite can be said about the Rays. While it is true that the pitching matchup swings slightly in favor of the Rays, that is not enough to justify the price tag that Tampa Bay is commanding in this matchup.

The best pick on the board is Toronto's money line. Berrios might not have a great outing, but as long as he does not get absolutely whacked, the Blue Jays will win this game. Toronto's offense might struggle early in the game, but it should come through in the later innings when Pepiot heads to the dugout. Take the Blue Jays to win outright.